Nutraveris
mardi 25 juillet 2017

Bifidobacterium longum subsp. infantis, Bifidobacterium bifidum et Lactobacillus helveticus sont bien tolérés par les nourrissons.

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The objective of this randomized, double-blind, placebo-controlled intervention study, was to evaluate the safety and tolerance of 3 probiotic strains (Bifidobacterium longum subsp. infantis R0033, Bifidobacterium bifidum R0071 and Lactobacillus helveticus R0052) in 221 healthy infants aged 3 to 12 months. They received either a placebo or one of the 3 probiotic strains (3×109cfu) daily during 8 weeks.

The results showed that changes in growth (weight, height and head circumference) were equivalent in all 4 groups. No SAEs were reported. Total number of AEs recorded was equivalent in all groups. Thus, the use of B. infantis, L. helveticus and B. bifidum in infancy is safe, and well tolerated.

 

safety and tolerance of 3 probiotic strains

Flow chart of the study

 

Manzano S, De Andrés J, Castro I, Rodríguez JM, Jiménez E, Espinosa-Martos I. Safety and tolerance of three probiotic strains in healthy infants: a multi-centre randomized, double-blind, placebo-controlled trial. Benef Microbes. 2017 May 30:1-10.

 

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