Nutraveris
Wednesday, November 15, 2017

Omega 3 fatty acids promote recovery after exercise.

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

This study examined the influence of adding long chain n-3 polyunsaturated fatty acids (n-3 PUFA) to a whey protein, leucine and carbohydrate containing beverage over a 6 week supplementation period on physiological markers of recovery measured over 3 days following eccentric exercise. Competitive soccer players were assigned to one of 3 conditions (2 × 200 mL):

  • FO (n=10) contained n-3 PUFA (1100 mg DHA/EPA: 550 mg DHA, 550 mg EPA), whey protein (15 g), leucine (1.8 g) and carbohydrate (20 g);
  • PRO (n=10) contained whey protein (15 g), leucine (1.8 g) and carbohydrate (20 g), and
  • CHO (n=10) contained carbohydrate (24 g).

Eccentric exercise consisted of unilateral knee extension/flexion contractions on both legs separately.

Muscle soreness, expressed as AUC during 72 hour recovery, was less in FO (1948 ±1091 mm×72 h) than PRO (4640 ±2654 mm×72h, p<0.05) and CHO (4495 ±1853 mm×72h p=0.10). Blood concentrations of creatine kinase, expressed as AUC, were ~60% lower in FO compared to CHO (p<0.05) and tended to be lower than PRO.

 

Muscle soreness

Muscle soreness (general soreness of the dominant leg), expressed as raw values over time during the overall 72 h recovery period following an intense bout of eccentric exercise.

Data are expressed as means ± SEM.

* FO significantly different versus PRO and CHO.

** FO significantly different versus PRO.

*** FO significantly different versus CHO.

# significantly different versus PRE in corresponding supplement condition.

 

In conclusion, the addition of n-3 PUFA to a beverage containing whey protein, leucine and carbohydrate ameliorates the increase in muscle soreness and blood concentrations of creatine kinase following eccentric exercise in competitive soccer players.

 

Philpott JD, Donnelly C, Walshe IH, Dick J, Galloway SDR, Tipton KD, Witard OC. Adding Fish Oil to Whey Protein, Leucine and Carbohydrate Over a 6 Week Supplementation Period Attenuates Muscle Soreness Following Eccentric Exercise in Competitive Soccer Players. Int J Sport Nutr Exerc Metab. 2017 Sep 5:1-28.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Tuesday, November 14, 2017

Rosa damascena oil reduces sexual dysfunction in methadone-treated women.

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

Methadone therapy, provided to patients with opioid use disorder, is known to induce sexual dysfunction. This randomized, double-blinded and placebo-controlled study examined the effects of Rosa damascena oil in women with methadone –induced sexual dysfunction.

Rosa damascena

50 women have been enrolled. They received a placebo or 2 mL of R. damascena oil (17 mg citronellol) for 8 weeks. Over time, sexual function and happiness increased.

The R. damascena oil had beneficial effects on desire, arousal, and on sexual function, with a total Female Sexual Function Index score changing from 36.48 ± 8.32 to 48.88 ± 8.39. These effects were associated with reduction in prolactin and increases in progesterone and estradiol, even if no correlation between sexual function and sex hormones have been highlighted.

 

This study confirms therefore the beneficial effects of R. damascena oil on methadone-related sexual dysfunction that had already been reported in men. Further studies should now assess the effects of R. damascena oil on sexual dysfunctions related to other causes.

 

 

Farnia V, Tatari F, Alikhani M, Yazdchi K, Taghizadeh M, Sadeghi Bahmani D, Karbasizadeh H, Holsboer-Trachsler E, Brand S. Rosa Damascena oil improved methadone-related sexual dysfunction in females with opioid use disorder under methadone maintenance therapy – results from a double-blind, randomized, and placebo-controlled trial. J Psychiatr Res. 2017 Aug 16;95:260-268.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Thursday, November 9, 2017

A new botanical combination for joint pain: demonstration in rat.

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

Despite pharmacological progresses, the management of joint pain is still difficult, and new natural solution are required to improve the quality of life of patients. In this study, the effects of the combination of Morus alba, Scutellaria baicalensis and Acacia catechu have been examined in a rat model of osteoarthritis.

 

Osteoarthritis was induced by monoiodoacetate injections. Animals were then divided in 6 groups, and were treated for 6 weeks with. The 6 groups were: control (no injection), monoiodoacetate (no supplement), diclofenac (10 mg/kg, positive control), M. alba and A. catechu combination (UP1306, 400 mg/kg), S. baicalensis and A. catechu combination (UP446, 250 mg/kg), or the combination of the three plants (650 mg/kg).

 

Joint pain was reduced up to 70.3% at 6 weeks with the three plants, whereas lower pain reductions were measured by the other combinations and for diclofenac. Moreover, significant improvements in articular matrix integrity have been shown in animals receiving the full combination.

 

 

Thus, the combination of M. alba, S. baicalensis and A. catechu is effective for the management of osteoarthritis symptoms in rats. Further studies are now required to confirm these effects in humans.

 

 

Yimam M, Horm T, Wright L, Jiao P, Hong M, Brownell L, Jia Q. Cartilage Protection and Analgesic Activity of a Botanical Composition Comprised of Morus alba, Scutellaria baicalensis, and Acacia catechu. Evid Based Complement Alternat Med. 2017;2017:7059068.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Tuesday, November 7, 2017

An anti-aging dietary supplement provides a photo-protection.

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

This trial examined the photo-protective properties of an anti-ageing dietary supplement (Bend Skincare Anti-Aging formula, Bend Beauty Inc. Canada) in 28 adults.

The product (4 capsules) provided 1400 mg of EPA + DHA, 120 mg of gamma-linolenic acid, 5 mg of lutein, 2.5 mg of zeaxanthin and 1000 IU vitamin D3 per day for 8 weeks.

Skin on each subject’s back was exposed to a progressive sequence of timed ultraviolet (UV) radiation exposure doses at baseline, and after 4 and 8 weeks treatment to determine their minimal erythema dose (MED).

 

erythema

 

Results showed that the supplementation increased the MED at 4 and 8 weeks compared with baseline (p < 0.001), highlighting a photo-protective activity of the supplement.

This protection increased progressively between week 0 and week 4 and between weeks 4 and 8.

MED increased by 39% at week 4 and by 84% at week 8.

 

Therefore, the tested product provided significant photo-protection.

 

 

 

Morse NL, Reid AJ, St-Onge M. An open label clinical trial assessing the efficacy and safety of Bend Skincare Anti-Aging Formula on minimal erythema dose in skin. Photodermatol Photoimmunol Photomed. 2017 Sep 8.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Monday, November 6, 2017

Training regulation, November, the 14th, in Paris

The fundamentals of the European regulation

and its development:

Food supplements and health ingredients

Tuesday, November 14, 2017, in Paris

 

Inscription here

Full program here

 

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