Nutraveris
Tuesday, January 8, 2013
Category : NEWS | Author : experts
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EFSA has published a new statement on the safety of β-carotene use in heavy smokers, following a request by the European Commission.
The Scientific Panel on Food Additives and Nutrient Sources added to Food (ANS) was asked to review existing data on the possible link between the ingestion of β-carotene and cancer enhancement in heavy smokers and to provide advice on a daily intake of β-carotene that does not give rise to concerns about adverse health effects in heavy smokers.

A meta-analysis of randomized controlled trials (RCT) investigating β-carotene supplementation and cancer risk (Druesne-Pecollo et al., 2010)
has been taken into account. Those data showed :
– absence of any protective effect associated with β-carotene supplementation with regard to primary cancer risk
– an increased risk of lung cancers in individuals supplemented with β-carotene at dose levels equal to or greater than 20 mg/day
– no increased lung cancer incidence in heavy smokers at supplemental dose levels of β-carotene varying from 6 – 15 mg/day for about 5 up to 7 years.

The Panel concluded that exposure to β-carotene from its use as food additive and as food supplement at a level below 15 mg/day do not give rise to concerns about adverse health effects in the general population, including heavy smokers.

New EFSA’s statement on the safety of β-carotene use in heavy smokers
EFSA Journal 2012;10(12):2953. [7 pp.]

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