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Thursday, June 27, 2013
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This randomized placebo-controlled study has evaluated whether Ginkgo biloba extract reduce risk for Alzheimer disease (AD) in 2854 elderly patients who report memory complaints.
During 5 years, subjects received 120 mg of a standardized Ginkgo biloba extract twice per day (n = 1419), or placebo (n = 1435).

The results showed that groups did not differ for AD at years 1 or 2; for cumulative incidence of AD over 5 years (4.3% vs 5.2%, P = 0.31); or for such adverse events as death, stroke, hemorrhagic events, or cardiac disorders (all P = 0.55).

Ginkgo biloba extract did not reduce risk for Alzheimer disease in elderly patients who reported memory complaints.

Ginkgo biloba extract did not reduce risk for Alzheimer disease in elderly patients with memory complaints.
Hirsch C, Ann Intern Med. 2013 Jan 15;158(2):JC7

Monday, June 17, 2013
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EFSA is asked to provide by 31 October 2013 updated scientific opinion on dietary requirements of infants and young children and on the composition of milk baseddrinks and similar products intended for infants and young children:

– Infant formula and follow-on formula (up to 12 months): today regulated under
Directive 2006/141/EC
– « growing-up milks » / « toddlers’ milks » suitable for young children (12 months – 3 years): for which no specific composition requirements are set in European legislation, the EFSA opinion will inform the Commission when drafting the report on the necessity, if any of special provisions for these products, in the context of the future revision of the PARNUTS legal framework.
Thursday, June 13, 2013
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The aim of the study was to evaluate the effect of alpha-lipoic acid(ALA) on temporary threshold shift measured 2 minutes after the end of exposure (TTS(2)) induced by a 3 kHz tone in young normally hearing subjects.

30 young normal hearing volunteers served as control subjects. Individuals were randomly assigned to three groups. Group A (10 subjects) subjects were exposed to a 90 dB HL 3 kHz pure tone for 10 min. Group B (10 subjects) subjects were exposed to a 90 dB HL 3 kHz pure tone one hour after oral ingestion of 600 mg of ALA. Group C (10 subjects) were exposed to a 90 dB HL 3 kHz pure tone after 10 days of oral ingestion of 600 mg of ALA.
Statistical analysis showed that prior to the exposure the hearing thresholds did not differ significantly among the three groups. TTS(2) of group C was significantly lower that TTS2 of Groups A and B at 6 kHz (p=0.03), and TEOAEs amplitude change after noise exposure was lower for group C compared to Groups A (p=0.089) and B (p=0.03). A single dose of 600 mg of dose ALA did not induce any protection on the TTS(2) induced by a 90 dB HL 3 kHz tone, while 10 days of therapeutic dosage assumption of ALA was associated with significant protection at 6 kHz.
The results of this study show that a short course of ALA protects from TTS(2) in humans, and therefore further studies are needed to better define the role of ALA in the prevention of noise induced hearing loss.

Acta Otorhinolaryngol Ital. 2012 Dec;32(6):380-385
The effect of alpha-lipoic acid on temporary threshold shift in humans: a preliminary study.
Quaranta N, Dicorato A, Matera V, D’Elia A, Quaranta A

Wednesday, June 5, 2013
Category : News, NUTRILEGAL | Author : experts | Comment : No Comments
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Under Regulation (EC) No 1333/2008, EFSA must re-evaluate by 2020 all authorized food additives.

For the re-evaluation of food additives for 2013 and 2014, EFSA has launched a new call for data asking Member States and other stakeholders for two types of data for 51 food additives in total: figures from industry on the amounts of these additives they report using in their products; and data derived from analyses indicating actual levels of these additives found in foods and drinks from national food authorities, research institutions, academia, food industry and other stakeholders.

The deadlines for the submission of data on usage level and/or concentration data in food and beverages intended for human consumption concerning the food additives listed in the table below is July and November 2013: