Wednesday, July 17, 2013
Category : Non classé | Author : experts

This randomized, double-blind, multicentric, placebo-controlled study has assessed the efficacy of orally administered capsules containing the probiotics Lactobacillus rhamnosus GR-1 and Lactobacillus reuteri RC-14 in 544 healthy women diagnosed with bacterial vaginosis.
Subjects received either probiotic (n=395 subjects) or identical-looking placebo capsules (n=149) per day over a period of 6 weeks.

Results showed that after this period, restitution to balanced vaginal microbiota was reported in 40 subjects (26.9%) in the placebo group, compared to 243 subjects (61.5%) in the probiotic group. Differences between groups were statistically significant at p<0.001. After the additional 6 weeks of follow up, normal vaginal microbiota were still present in more than half (51.1%) of subjects in the probiotic group, but only in around one-fifth (20.8%) of subjects who were taking placebo (p<0.001). In conclusion, oral probiotics could be an alternative, side effect-free treatment for bacterial vaginosis and other vaginal infections.

Eur J Obstet Gynecol Reprod Biol. 2013 Feb 7. pii: S0301-2115(13)00013-4.
Efficacy of orally applied probiotic capsules for bacterial vaginosis and other vaginal infections: a double-blind, randomized, placebo-controlled study.
Vujic G, Jajac Knez A, Despot Stefanovic V, Kuzmic Vrbanovic V.

Leave a Reply