Thursday, September 8, 2016

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Overweight troubles are more and more common and efficient solutions are rare. Nevertheless, some plant extracts have beneficial effects on weight loss. In order to help overweight people, a randomized, double-blind, placebo-controlled study assessed the efficacy of Meratrim, a blend of 2 ingredients (plant extracts): flower heads from Sphaeranthus indicus and fruit rinds from purple mangosteen (Garcinia mangostana) in a 3:1 ratio. A total of 60 overweight subjects (mean BMI 28.3 kg/m²) received 800 mg of Meratrim or a placebo for 16 weeks. They consumed about 2000 kcal/day throughout the study period and walk 5 days a week for 30 min daily.

The results of the measured parameters are presented hereunder.

 The results of the measured parameters

At the end of the study, statistically significant reductions were measured in body weight (-5.09 vs. -1.1 kg; p < 0.0001), BMI (-1.91 vs. -0.43 kg/m²; p < 0.0001), waist (-9.97 vs. -3.71 cm; p < 0.001) and hip size (-10.38 vs. -5.11 cm; p < 0.0001) in the Meratrim versus the placebo group. Additionally, a significant change in serum LDL (-14.79 vs. 6.25 mg/dL; p < 0.0001), triglycerides (-43.62 vs. -13.68 mg/dL; p < 0.001) and total cholesterol (-20.0 vs. -0.75 mg/dL; p = 0.0002) was observed in the Meratrim cohort compared to the placebo. No supplementation related adverse events were noted during the study. The study findings suggest that Meratrim is well-tolerated and is an effective ingredient for weight management in healthy overweight subjects.

Kudiganti V, Kodur RR, Kodur SR, Halemane M, Deep DK.

Efficacy and tolerability of Meratrim for weight management: a randomized, double-blind, placebo-controlled study in healthy overweight human subjects.

Lipids Health Dis. 2016 Aug 24;15(1):136.


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