Nutraveris
Wednesday, November 2, 2016
Category : News, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, informs you:

 

Fenugreek seeds (Trigonella foenum graecum) are known to exhibit potent hypoglycaemic activities. The mechanism of action remains unclear, but recent studies suggest that furostanolic saponins may be involved. In order to clarify the effects of furostanolic saponins, the effects of a proprietary fenugreek extract (FenufuroTM) (40% furostanolic sanonins) have been examined in subjects with type 2 diabetes.

fenugrec

This study was randomized, double-blinded and placebo-controlled. 154 subjects have received a placebo or FenfuroTM (500 mg twice daily) for 90 days. The supplementation has reduced both fasting and post-prandial plasma sugar levels. HbA1c levels has been reduced in both groups. Moreover, fasting and post-prandial C-peptide levels have been increased in the supplemented group, while no change has been observed in the placebo group. Moreover, more subjects in the supplemented group reduced their anti-diabetic therapy in comparison to the placebo group (48.8% vs. 18.05%). Finally, no significant adverse event were observed. This study confirms therefore the beneficial effects of fenugreek seed extracts, and suggests that furostanolic saponins may be involved in this anti-diabetic activity.

 

Verma N, Usman K, Patel N, Jain A, Dhakre S, Swaroop A, Bagchi M, Kumar P, Preuss HG, Bagchi D. A multicenter clinical study to determine the efficacy of a novel fenugreek seed (Trigonella foenum-graecum) extract (Fenfuro™) in patients with type 2 diabetes. Food Nutr Res. 2016 Oct 11;60:32382.

 

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