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Reduction in blood pressure with pomegranate juice: a meta-analysis

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Pomegranate has been claimed to reduce the risk of cardiovascular diseases. However, the effects of pomegranate remain unclear. This meta-analysis aimed therefore to clarify the effects of pomegranate juice on blood pressure.

8 randomized and controlled studies have been included in the analysis, for a total of 574 individuals. They received pomegranate juice for 2 weeks to 18 months. Two studies were conducted in healthy volunteers, whereas the 6 other studies were conducted in patients with cardiovascular risk factors or cardiovascular diseases.

Results showed reductions in systolic (-4.96 mmHg, 95% CI: -7.67 to -2.25, p < 0.001) and diastolic blood pressure (-2.01 mmHg, 95% CI: -3.71 to -0.31, p = 0.021) after pomegranate juice. The effects of pomegranate juice on systolic blood pressure were independent of supplementation length (<12 weeks vs. > 12 weeks) and of dose consumed (<240 cc vs. >240 cc).

The authors concluded that pomegranate juice effectively reduce blood pressure and propose to include this juice in heart-healthy diets.


Sahebkar A, Ferri C, Giorgini P, Bo S, Nachtigal P, Grassi D. Effects of Pomegranate Juice on Blood Pressure: A Systematic Review and Meta-analysis of Randomized Controlled Trials. Pharmacol Res. 2016 Nov 22. pii: S1043-6618(16)30784-8.

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