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Tuesday, December 27, 2016
Category : News, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

This clinical trial aimed to evaluate long-term chamomile (Matricaria chamomilla L.) use for prevention of generalized anxiety disorder symptom relapse.

A total of 179 patients with a primary diagnosis of moderate-to-severe generalized anxiety disorder were enrolled for this study.

During Phase 1, eligible participants received 12 weeks of open-label therapy with chamomile pharmaceutical grade extract 1500 mg.

During Phase 2, treatment responders were given either 26 weeks of continuation chamomile therapy or placebo in a double-blinded, placebo-substitution design.

Mean time to relapse was 11.4 ± 8.4 weeks for chamomile and 6.3 ± 3.9 weeks for placebo. During follow-up, chamomile participants maintained significantly lower generalized anxiety disorder symptoms than placebo (p = 0.0032), with significant reductions in body weight (p = 0.046) and mean arterial blood pressure (p = 0.0063).

chamomille-and-anxiety-disorder

Mean weight change in kg

Long-term chamomile was safe and significantly reduced moderate-to-severe generalized anxiety disorder symptoms, but did not significantly reduce rate of relapse.

 

Mao JJ, Xie SX, Keefe JR, Soeller I, Li QS, Amsterdam JD. Long-term chamomile (Matricaria chamomilla L.) treatment for generalized anxiety disorder: A randomized clinical trial. Phytomedicine. 2016 Dec 15;23(14):1735-1742.

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