Thursday, February 23, 2017

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This dose-response meta-analysis was investigated to assess the association between dietary total flavonoids intake and the risk of mortality.

Ten studies were included. The relative risk (RR) of all-cause mortality for the highest versus lowest category of total flavonoids intake was 0.82 (95% confidence interval (CI): 0.72-0.92). Dose-response analysis showed that those consuming 200mg/d of total flavonoids had the lowest risk of all-cause mortality.


Dietary flavonoids intake

Relationship between falvonoïds and all-cause mortality in dose-response analysis



Furthermore, a marginally significant association was found between dietary total flavonoids consumption and risk of death from CVD (summary RR: 0.85; 95% CI: 0.70-1.03; P = 0.099) and coronary heart diseases (CHD) (summary RR: 0.74; 95% CI: 0.54-1.02; P = 0.069), respectively.

Authors concluded the meta-analysis provides strong evidence for the recommendation of consuming flavonoids-rich food to reduce risks of mortality from all causes as part of a healthy diet among general adults.



Liu XM, Liu YJ, Huang Y, Yu HJ, Yuan S, Tang BW, Wang PG, He QQ. Dietary total flavonoids intake and risk of mortality from all causes and cardiovascular disease in the general population: a systematic review and meta-analysis of cohort studies. Mol Nutr Food Res. 2017 Jan 5.


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