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Thursday, March 30, 2017
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The present randomized, double-blind, placebo-controlled clinical trial evaluated the weight loss effect of a polysaccharide-rich food supplement, LipiGo®, comprising a specific beta-glucan-chitin-chitosan fraction (BGCC) obtained from the chemical hydrolysis of Saccharomyces cerevisiae, resulting as a by-product of the brewing process.

A total of 56 overweight and obese subjects (BMI, 25-35 kg/m²) were given placebo or BGCC (3 g/d), for 12 weeks. Body weight increased in the placebo group compared to baseline (ITT: 1.0 Kg, p<0.001; PP: 1.5 kg, p=0.003), while it was slightly lowered in the BGCC group (ITT: -0.8 kg, p=0.210; PP: -1.1 kg, p=0.182). BGCC but not placebo consumption also resulted in a reduction of waist circumference and body fat in BGCC compared to baseline.

LipiGo® supplementation in overweight and obese subjects decrease weight, BMI and waist circumference

Δ Change in weight, BMI and waist perimeter from baseline to 12 weeks in participants receiving the placebo or BGCC.

Results suggest that daily supplementation of specific beta-glucan-chitin-chitosan fraction may be useful for improving body weight and waist circumference in overweight and obese subjects.

 

Santas J, Lázaro E, Cuñé J. Effect of a polysaccharide-rich hydrolysate from Saccharomyces cerevisiae (LipiGo®) in body weight loss: Randomized, double-blind, placebo-controlled clinical trial in overweight and obese adults. J Sci Food Agric. 2017 Mar 2.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Tuesday, March 28, 2017
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

This study aim was to investigate the effect of chondroitin sulfate (CS) on brain response to knee painful stimulation in patients with knee osteoarthritis using functional magnetic resonance imaging (fMRI).

functional magnetic resonance imaging (fMRI)

Twenty-two patients received CS (800mg/day) and 27 patients placebo, and were assessed at baseline and after 4 months of treatment.

Results show fMRI of patella pain showed significantly greater activation reduction under CS compared with placebo in the region of the mesencephalic periaquecductal gray.

The CS group, additionally showed pre/post-treatment activation reduction in the cortical representation of the leg.

Authors concluded fMRI was sensitive to objectify CS effects on brain response to painful pressure on patellofemoral cartilage, which is consistent with the known CS action on chondrocyte regeneration.

Monfort J, Pujol J, Contreras-Rodríguez O, Llorente-Onaindia J, López-Solà M, Blanco-Hinojo L, Vergés J, Herrero M, Sánchez L, Ortiz H, Montañés F, Deus J, Benito P. Effects of chondroitin sulfate on brain response to painful stimulation in knee osteoarthritis patients. A randomized, double-blind, placebo-controlled functional magnetic resonance imaging study. Med Clin (Barc). 2017 Feb 22. pii: S0025-7753(17)30042-8.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Monday, March 27, 2017
Category : NEWS, TRAINING | Author : experts | Comment : No Comments
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La Baleine Blanche, formation NUTRAVERIS

Notre dernière formation détaillant les fondamentaux de la réglementation européenne et de ses évolutions s’est tenue à Paris le 21 mars 2017.

A bord de la péniche La Baleine Blanche, cette formation a abordé les spécificités des compléments alimentaires, des ingrédients santé et produits pour sportifs.

Formation NUTRAVERIS, salle séminaire La Baleine Blanche

Nos différents intervenants ont eu le plaisir d’animer cette journée et de répondre aux questions d’une assemblée constituée de spécialistes du monde du complément alimentaire, pharmaceutique, agroalimentaire et cosmétique:

Amélie Denis, Responsable du Pôle Réglementaire, Ingénieur agroalimentaire

Thomas Pauquai, Responsable du Pôle Scientifique, Docteur en physiologie et physiopathologie

Cédric Bourges, dirigeant fondateur, Docteur en Pharmacie complété d’un DEA de Pharmacologie, d’un MBA et d’un Mastère en Droit Pharmaceutique

 

Formation NUTRAVERIS, salon supérieur La Baleine Blanche

 

Agréé en tant qu’organisme de formation continue professionnelle, les formations du cabinet Nutraveris peuvent être prises en charge par la direction régionale du travail, de l’emploi et de la formation professionnelle.

Si vous souhaitez plus d’informations sur les prochaines formations, n’hésitez pas à nous contacter et à prendre date.

Thursday, March 23, 2017
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The aim of this randomized, double-blind, placebo-controlled study was to examine the effects of prebiotic supplementation on appetite control and energy intake in 42 children with overweight and obesity.

 

Children were assigned to 8 g oligofructose-enriched inulin/d or placebo (maltodextrin), for 16 weeks. Compared with placebo, prebiotic intake resulted in significantly higher feelings of fullness (p = 0.04). Compared with placebo, prebiotic supplementation significantly reduced energy intake at the week 16 breakfast buffet in 11- and 12-years-olds (p = 0.04) but not in 7- to 10-y-olds. Fasting adiponectin (p = 0.04) and ghrelin (p = 0.03) increased at 16 weeks with the prebiotic compared with placebo. In ITT analysis, there was a trend for prebiotic supplementation to reduce BMI z score to a greater extent than placebo (-3.4%; p = 0.09).

 

Prebiotic supplementation in children with overweight and obesity improves appetite regulation.

Figure: Change (from baseline to 16 weeks) in fullness ratings taken before and after a breakfast buffet in participants receiving a prebiotic (n = 21) or placebo (n = 19). Values are means ± SEMs. *Different from placebo, p<0.05

 

 

Independent of other lifestyle changes, prebiotic supplementation in children with overweight and obesity improved subjective appetite ratings. This simple dietary change has the potential to help with appetite regulation in children with obesity.

 

Hume MP, Nicolucci AC, Reimer RA. Prebiotic supplementation improves appetite control in children with overweight and obesity: a randomized controlled trial. Am J Clin Nutr. 2017 Feb 22.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Tuesday, March 21, 2017
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
Tags:

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The purpose of this double-blind, placebo-controlled study was to examine the effect of two fish oil supplements, one high in EPA (750 mg EPA, 50 mg DHA) and one low in EPA (150 mg EPA, 100 mg DHA), taken acutely as a recovery strategy following exercise-induced muscle damage.

27 physically active males (26 ± 4 year, 1.77 ± 0.07 m, 80 ± 10 kg) completed 100 plyometric drop jumps to induce muscle damage. Immediately after the damaging protocol, volunteers ingested either a placebo (Control), a low-EPA fish oil (Low EPA) or a high-EPA fish oil (High EPA) at a dose of 1 g per 10 kg body mass.

 

Squat jump performance

Squat jump performance before and up to 96h after damaging exercise. *Denotes a significant group effect.

 

A significant group main effect was observed for squat jump, with the High EPA group performing better than Control and Low EPA groups (average performance decrement, 2.1, 8.3 and 9.8%, respectively), and similar findings were observed for countermovement jump performance, (average performance decrement, 1.7, 6.8 and 6.8%, respectively, p = 0.07).

 

 

This study indicates that an acute dose of high-EPA fish oil may ameliorate the functional changes following exercise-induced muscle damage.

 

Jakeman JR, Lambrick DM, Wooley B, Babraj JA, Faulkner JA. Effect of an acute dose of omega-3 fish oil following exercise-induced muscle damage. Eur J Appl Physiol. 2017 Feb 17.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87