Tuesday, April 18, 2017
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

Probiotics are well-known for their beneficial effects on gut microflora. Two meta-analyzes have examined the scientific evidences substantiating the effect of probiotics on inflammatory bowel diseases or gastrointestinal discomfort.


Probiotics may have no effect on Crohn’s disease (9 trials, p = 0.07), but have a significant beneficial effects in children with inflammatory bowel diseases (3 trials, p = 0.01). Moreover, studies have shown that probiotics in patients with ulcerative colitis have significant effects (18 trials, p =0.007).

In the general population, the consumption of fermented milk that includes Bifidobacterium lactis CNCM I-2494 and lactic acid bacteria is associated with a significant improvement in overall gastrointestinal discomfort compared to control (OD=1.48, 95% CI: 1.07-2.05). Fermented milk was also superior to control in reducing digestive symptoms.

These meta-analyzes confirm consequently the interest of probiotics for the management of digestive health, both in the general population and in patients with inflammatory bowel diseases.

Eales J, Gibson P, Whorwell P, Kellow J, Yellowlees A, Perry RH, Edwards M, King S, Wood H, Glanville J. Systematic review and meta-analysis: the effects of fermented milk with Bifidobacterium lactis CNCM I-2494 and lactic acid bacteria on gastrointestinal discomfort in the general adult population. Therap Adv Gastroenterol. 2017 Jan;10(1):74-88.

Ganji-Arjenaki M, Rafieian-Kopaei M. Probiotics Are a Good Choice in Remission of Inflammatory Bowel Diseases: A Meta Analysis and Systematic Review. J Cell Physiol. 2017 Mar 15.


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