Friday, May 5, 2017
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments

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This study aim was to examine the association of maternal plasma polyunsaturated fatty acids (PUFAs) in pregnancy with 18-mo postpartum weight retention (PPWR) in a multiethnic Asian cohort of pregnant women (n = 653).

postpartum weight retention



The median retained weight of women was 0.90 kg (IQR: -1.40, 3.25) at 18 mo postpartum. Of 653 women, 544 women (83.3%) had PPWR of <5 kg and 109 (16.7%) had PPWR of ≥5 kg. In adjusted linear regression models, higher plasma eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and total ω-3 (n-3) PUFA concentrations were associated with lower PPWR [EPA: β = -0.62 kg/1% increase of total FAs (95% CI: -1.18, -0.05); DHA: β = -0.24 kg/1% increase (95% CI: -0.45, -0.02); total ω-3 PUFAs: β = -0.20 kg/1% increase (95% CI: -0.36, -0.03)], whereas a higher ratio of plasma ω-6-to-ω-3 PUFAs was associated with a higher PPWR [β = 0.21 kg/unit increase (95% CI: 0.05, 0.36)].

Authors concluded higher plasma percentages of ω-3 PUFAs and a lower ratio of ω-6-to-ω-3 PUFAs in the late-second trimester of pregnancy are associated with less weight retention at 18 mo postpartum.




Loy SL, Ng MJ, Cheung YB, Godfrey KM, Calder PC, Lek N, Yap F, Müller-Riemenschneider F, Natarajan P, Chong YS, Tan KH, Shek LP, Chong MF, Chan JK. Plasma ω-3 fatty acids in pregnancy are inversely associated with postpartum weight retention in a multiethnic Asian cohort. Am J Clin Nutr. 2017 Mar 22.


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