Tuesday, May 9, 2017
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments

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In the present study using DJ-1β(Δ93) flies, a Parkinson’s disease model in Drosophila, has been demonstrated the therapeutic effect of spirulina and its active component C-phycocyanin (C-PC) in the improvement of lifespan and locomotor behavior.




Dietary supplementation of spirulina significantly improves the lifespan and locomotor activity of paraquat-fed DJ-1β(Δ93) flies.

Furthermore, supplementation of spirulina and C-PC individually and independently reduced the cellular stress marked by deregulating the expression of heat shock protein 70 and Jun-N-terminal kinase signaling in DJ-1β(Δ93) flies.

A significant decrease in superoxide dismutase and catalase activities in spirulina-fed DJ-1β(Δ93) flies tends to indicate the involvement of antioxidant properties associated with spirulina in the modulation of stress-induced signaling and improvement in lifespan and locomotor activity in Drosophila DJ-1β(Δ93) flies.


Authors concluded results suggest that antioxidant boosting properties of spirulina can be used as a nutritional supplement for improving the lifespan and locomotor behavior in Parkinson’s disease.



Kumar A, Christian PK, Panchal K, Guruprasad BR, Tiwari AK. Supplementation of Spirulina (Arthrospira platensis) Improves Lifespan and Locomotor Activity in Paraquat-Sensitive DJ-1βΔ93 Flies, a Parkinson’s Disease Model in Drosophila melanogaster. J Diet Suppl. 2017 Sep 3;14(5):573-588.


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