Nutraveris
Thursday, January 24, 2019
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts
Tags:

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The aim of this triple-blind, randomized placebo-controlled trial was to survey the effect of saffron supplementation on anti-HSP70, high-sensitivity C-reactive protein (hs-CRP) and spirometry test in patients with allergic asthma.

To do so, 80 patients with mild and moderate allergic asthma were randomized to receive either two capsules of saffron (100 mg/d) or placebo (control group) for 8 weeks.

 

Saffron supplementation in patients with allergic asthma

Within- and between-group comparisons of the changes from baseline to endpoint measures for hs-CRP and anti-HSP70 in saffron and placebo groups of asthmatic patients

Results showed that saffron significantly reduced the hs-CRP (p < 0.001) and anti-HSP70 (p < 0.001) concentrations compared to placebo. In spirometry test, forced expiratory volume in first second (FEV1), forced vital capacity (FVC), FEV1/FVC ratio and forced expiratory flow were 25-75%. (FEF 25-75) increased significantly in saffron in comparison to placebo group (p < 0.05).

Authors concluded that saffron supplementation in patients with allergic asthma decreased significantly anti-HSPs 70 and hs-CRP and also improved some spirometry test factors.

 

Hosseini SA, Zilaee M, Shoushtari MH, Ghasemi Dehcheshmeh M. An evaluation of the effect of saffron supplementation on the antibody titer to heat-shock protein (HSP) 70, hsCRP and spirometry test in patients with mild and moderate persistent allergic asthma: A triple-blind, randomized placebo-controlled trial. Respir Med. 2018 Dec; 145:28-34.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Leave a Reply