Nutraveris
Thursday, May 2, 2019
Category : NEWS, INGREDIENTS, CLINICAL EVIDENCE | Author : experts
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Our Artificial Intelligence solutions, developed by our experts, NOL Datasolution to Create & NOL Compliance to Launch your products, inform you :  

 

Vitamins B are frequently used to improve cognitive function, even if strong clinical evidences are lacking. The aim of this systematic review and meta-analysis was to examine the available data on vitamin B supplementation and cognitive functions in the elderly.

 

Vitamin B supplementation for cognitive function: lack of effect in the elderly.

The authors compiled 31 randomized and placebo-controlled study examining the effects of vitamins B (B6, B9 and/or B12) in older adults with or without cognitive impairment. 10 studies have been conducted in subjects with cognitive impairment (1925 participants, whereas 21 other studies have been conducted in healthy subjects (15,104 participants). All studies except two have failed to highlight any significant effects of vitamins B supplementations. No improvement in the Mini-mental State Examination (MMSE) score has been noted for subjects with or without cognitive impairment.

Therefore, it seems that, despite their recognition by EFSA as important for normal psychological function, vitamins B supplementations are not effective for improving cognitive functions in elderly with or without cognitive impairment.

Ford AH, Almeida OP. Effect of Vitamin B Supplementation on Cognitive Function in the Elderly: A Systematic Review and Meta-Analysis. Drugs Aging. 2019 Apr 4.

 

NUTRAVERIS is the Leading European consultancy on Regulatory & Scientific affairs in Nutrition and Health, founded 13 years ago, to help you formulate, ensure the compliance and substantiation of your products in the 28 EU Member States. 

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