Thursday, May 16, 2019
Category : NEWS, INGREDIENTS, CLINICAL EVIDENCE | Author : experts | Comment : No Comments

Our Artificial Intelligence solutions, developed by our experts, NOL Datasolution to Create & NOL Compliance to Launch your products, inform you :  


The aim of this double-blinded, randomized and placebo-controlled study was to examine the effects of an Andrographis paniculata extract in patients with knee osteoarthritis. 103 patients have been enrolled and received a placebo of the extract (ParActin®, 300 or 600 mg/day) for 84 days.

An Andrographis paniculata supplementation reduces joint pain in patients with knee osteoarthritis.

The both doses of supplement have reduced joint pain at days 28, 56 and 84 in comparison to control. Moreover, significant improvements in WOMAC stiffness scores and function scores, as in fatigue score have been measured in both supplemented groups compared to placebo. Finally, quality of life, assessed by the SF-36 questionnaire, and the score of the Functional Assessment of Chronic Illness Therapy have been improved in both supplemented groups.

In conclusion, this study shows that ParActin®, an Andrographis paniculata extract, can reduce joint pain and improve joint function in patients with knee osteoarthritis.


Hanckle JL, Srivastav S, Caceres DD, Burgos RA. A double-blind, randomized, placebo-controlled study to asses the efficacy of Andrographis paniculata standardized extract (ParActin®) on pain reduction in subjects with knee osteoarthritis. Phytother Res. 2019 Apr 10.


NUTRAVERIS is the Leading European consultancy on Regulatory & Scientific affairs in Nutrition and Health, founded 13 years ago, to help you formulate, ensure the compliance and substantiation of your products in the 28 EU Member States. 

 Thanks to our strong know-how and experience of regulatory compliance, notifications, novel foods, health claims, medical writing,…We, as experts, created Artificial Intelligence solutions, that we use in our everyday missions:

-NOL Datasolution to CREATE new products thanks to Regulatory, Scientific & Marketing data.

-NOL Compliance to LAUNCH products into the different EU member states thanks to automated Compliance analysis, Labeling generation and Monitoring & updating at anytime.

More information on

Contact our Scientific & Regulatory experts at NUTRAVERIS, +33 2 96 76 54 87