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Pomegranate seed oil is traditionally used for the treatment of various disorders, including menopausal disorders. The purpose of this trial was to confirm the beneficial effects of pomegranate seed oil on in women with menopausal discomfort.
78 women with menopausal symptoms for an average time of 46 months received 1000 mg of pomegranate seed oil for 8 weeks. The β-sitosterol content of the supplement was 6.3 mg/1000 mg. A significant decrease in menopausal symptoms has been measured, notably regarding hot flashes (score reduced from 2.32 ± 1.04 to 1.41 ± 1.07, p < 0.001).
Similarly, urogenital tract symptoms (i.e. vaginal dryness) has been also reduced (2.32 ± 1.04 to 0.85 ± 1.19, p < 0.001).
Results showed also a good tolerability of the product, and no change in 17β estradiol has been reported.
Thus, pomegranate seed oil may be useful for the management of menopausal symptoms. However, larger well-designed studies are required to confirm the interest of pomegranate seed oil.
Huber R, Gminski R, Tang T, Weinert T, Schulz S, Linke-Cordes M, Martin I, Fischer H. Pomegranate (Punica granatum) Seed Oil for Treating Menopausal Symptoms: An Individually Controlled Cohort Study. Altern Ther Health Med. 2017 Mar;23(2):28-34.
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