Nutraveris

Category 'News'

Tuesday, February 21, 2017

Lactobacillus brevis intake improves skin hydration conditions.

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The aim of this randomized, double-blind, placebo-controlled study was to investigate the effect of heat-killed Lactobacillus brevis (L. brevis) SBC8803 (SBL88™) intake on skin hydration conditions. The subjects (126 people aged between 21 and 59 years) with slightly higher levels of transepidermal water loss (TEWL) on the forearm were allocated to 3 different groups: placebo or heat-killed L. brevis SBC8803 at a daily dose of 25 or 50 mg, for 12 weeks.

Schedule for the study: Lactobacillus brevis intake & skin hydration

The results revealed that marginal differences were observed in TEWL at the neck in the 25 mg/day group at week 8 and at the lower eye region in the 50 mg/day group at week 4 (p=0.05 and 0.09, respectively, compared with the placebo group). A significant increase in corneal hydration was also observed at the neck in the 25 mg/day group at week 12 (p=0.06, as compared with the placebo group). In the analysis of the subpopulations whose habitual frequency of taking lactic fermentation products was less than once per week, the levels of corneal hydration at the neck (in the 50 mg/day group) and lower eye region (in the 25 mg/day group) were significantly increased at week 12 (p<0.05).

In conclusion, the results of this investigation suggest that oral intake of heat-killed L. brevis SBC8803 is effective at improving skin hydration conditions in populations with low habitual frequency of taking lactic fermentation products.

        

Ogawa M, Saiki A, Matsui Y, Tsuchimoto N, Nakakita Y, Takata Y, Nakamura T. Effects of oral intake of heat-killed Lactobacillus brevis SBC8803 (SBL88™) on dry skin conditions: A randomized, double-blind, placebo-controlled study. Exp Ther Med. 2016 Dec;12(6):3863-3872.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Thursday, February 16, 2017

Beneficial effect of Lactobacillus rhamnosus on impact of social stress.

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

In this study was investigated the potential for microbe-induced gut-to-brain signalling to modulate the impact of stress on host behaviour and immunoregulation.

 

social stress

Male C57BL/6 mice treated orally over 28 days with either Lactobacillus rhamnosus (JB-1™) or vehicle were subjected to chronic social defeat and assessed for alterations in behaviour and immune cell phenotype.

Treatment with JB-1 decreased stress-induced anxiety-like behaviour and prevented deficits in social interaction with conspecifics. However, JB-1 did not alter development of aggressor avoidance following social defeat. Microbial treatment attenuated stress-related activation of dendritic cells while increasing IL-10+ regulatory T cells. Furthermore, JB-1 modulated the effect of stress on faecal metabolites with neuroactive and immunomodulatory properties. Exposure to social defeat altered faecal microbial community composition and reduced species richness and diversity, none of which was prevented by JB-1. Stress-related microbiota disruptions persisted in vehicle-treated mice for 3 weeks following stressor cessation.

Authors concluded these data demonstrate that despite the complexity of the gut microbiota, exposure to a single microbial strain can protect against certain stress-induced behaviours and systemic immune alterations without preventing dysbiosis.

 

Bharwani A, Mian MF, Surette MG, Bienenstock J, Forsythe P. Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress. BMC Med. 2017 Jan 11;15(1):7.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Wednesday, February 15, 2017

(Français) Les fondamentaux de la réglementation: formation à Paris le 21 mars

Sorry, this entry is only available in French.

Tuesday, February 14, 2017

Stinging nettle: interest of a supplementation in type 2 diabetics.

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

Urtica dioica

 

This randomized, double-blinded and placebo-controlled trial examined the effects of an hydro-alcoholic extract of Urtica dioica L. in patients with type 2 diabetes, by focusing on blood glucose control, blood lipids, hepatic enzymes, and nitric oxide levels. 50 women with type 2 diabetes have been enrolled. For 8 weeks, they received a placebo or 5 mL/d of the U. dioica extract (60% ethanol/water v/v).

In comparison to placebo, the extract reduced blood glucose and triglycerides levels (p <0.01 and p < 0.05 respectively).

Moreover, HDL-cholesterol levels have been increased in the U. dioica group (p < 0.05 in comparison to placebo), whereas LDL-cholesterol has not been affected by the supplementation.

In addition, the liver enzyme SGPT (serum glutamic pyruvic transaminase) has been reduced (p < 0.05), while nitric oxide and superoxide dismutase levels have been increased (p < 0.01 and p < 0.05 respectively).

Therefore, these results suggest that stinging nettle, generally used for joint health, can also be interesting for subjects with type 2 diabetes.

 

 

Amiri Behzadi A, Kalalian-Moghaddam H, Ahmadi AH. Effects of Urtica dioica supplementation on blood lipids, hepatic enzymes and nitric oxide levels in type 2 diabetic patients: A double blind, randomized clinical trial. Avicenna J Phytomed. 2016 Nov-Dec;6(6):686-695.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Monday, February 13, 2017

New EFSA health claim guidance : Nutraveris’s comments highlighted by EFSA

EU health claim specialists say EFSA guidance issued last week clarifies application procedures but changes nothing of the infamous pharma-style scientific requirements that have denied 1000s of claims across the EU bloc of 28 nations…

efsa

Find below the publication of NUTRAINGREDIENT:

http://www.nutraingredients.com/Regulation-Policy/Industry-response-New-EFSA-health-claim-guidance-makes-applying-easier-but-science-requirements-remain-the-same