Nutraveris

Category 'News'

Monday, January 16, 2017

Branched-chain amino acids improve performances in cyclists.

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

This placebo-controlled study examined if supplementing trained cyclists with branched amino acids during training season affected select body composition, performance, and immune variables. Cyclists received either 12 g/day (6 g/d L-Leucine, 2 g/d L-Isoleucine and 4 g/d L-Valine) of either branched-chain amino acids (BCAAs, n = 9) or a maltodextrin placebo (PLA, n = 9) over a 10-week training season.

A significant interaction existed for body mass-normalized relative peak power (19% increase in the BCAA group pre- to post-study, p=0.01), and relative mean power (4% increase in the BCAA group pre- to post-study, p=0.01).

A significant interaction for neutrophil number existed (p=0.04), as there was a significant 18% increase within the PLA group from the pre- to post-study time point (p=0.01). Chronic BCAA supplementation improves sprint performance variables in endurance cyclists.

 

Effects of chronic BCAA supplementation on Wingate variables in cyclists

Effects of chronic BCAA supplementation on Wingate variables in cyclists

Pre-study (pre) and 10-week post-study (post) Wingate variables.

panel a: A group × time interaction was observed for peak power (p = 0.02), and the BCAA group increased peak power by 20 % compared to the pre-study time point (**p = 0.01) .

panel b: A group × time interaction was also observed for relative peak power (p = 0.01), and the BCAA group increased relative peak power by 19 % compared to the pre-study time point (**p = 0.01) .

panel c: A group × time interaction was observed for mean power (p = 0.01), and the BCAA group increased mean power by 4 % compared to the pre-study time point (**p = 0.01) .

panel d: No group × time interactions was observed for relative mean power (MP).

 

Given that BCAA supplementation blunted the neutrophil response to intense cycling training, BCAAs may benefit immune function during a prolonged cycling season.

Kephart WC, Wachs TD, Mac Thompson R, Brooks Mobley C, Fox CD, McDonald JR, Ferguson BS, Young KC, Nie B, Martin JS, Company JM, Pascoe DD, Arnold RD, Moon JR, Roberts MD. Ten weeks of branched-chain amino acid supplementation improves select performance and immunological variables in trained cyclists. Amino Acids. 2016 Mar;48(3):779-89.

 

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Thursday, January 12, 2017

DHA has beneficial effect on fat mass in subjects with type II diabetes mellitus.

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The aim of this randomized, placebo-controlled study was to investigate the impact of docosahexaenoic acid (DHA)-rich fish oil supplementation on body composition, in subjects with type 2 diabetes mellitus (T2DM), for 8 weeks.

Diabetes

Glycemic control was not affected by the intervention.

The supplementation with DHA-rich fish oil decreased waist circumference (p < 0.001), body fat mass (p = 0.01), body fat percent (p = 0.04), and viscera fat rating (p = 0.02) as well as trunk fat mass (p = 0.04).

Weight, body mass index, fat-free mass, adiponectin level, and PPARγ gene expression changes showed no significant difference.

DHA-rich fish oil supplementation favorably modulated body composition in patients with T2DM and could be useful to reduce visceral obesity.

Mansoori A, Sotoudeh G, Djalali M, Eshraghian MR, Keramatipour M, Nasli-Esfahani E, Shidfar F, Alvandi E, Toupchian O, Koohdani F. Docosahexaenoic Acid-Rich Fish Oil Supplementation Improves Body Composition without Influence of the PPARγ Pro12Ala Polymorphism in Patients with Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. J Nutrigenet Nutrigenomics. 2015;8(4-6):195-204.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

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  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

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Monday, January 9, 2017

Efficacy of Perna canaliculus in children with attention-deficit hyperactivity disorder.

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

PCSO-524® is a standardized lipid extract of the New-Zealand green-lipped mussel (Perna canaliculus) known for its anti-inflammatory properties.

 

 

In this randomized, double-blinded, placebo-controlled study, PCSO-524® has been given to children and adolescents with attention-deficit hyperactivity disorder (ADHD, n =144). Participants receiving the extracts have consumed three (≤ 45 kg) or four (> 45 kg) capsules per day for 14 weeks. Each capsule (260 mg) provided 50 mg eicosatetraenoic acid, 7.3 EPA, 5.5 mg DHA, 100 mg of natural mono-unsaturated olive oil and 0.225 mg vitamin E.

 

Results did not report any significant effect of PCSO-524® in comparison to placebo on parental reports of hyperactivity, inattention and impulsivity in children aged 6 to 14 years.

However, repeated measures ANOVA showed significant improvements in hyperactivity (p = 0.04), attention (p = 0.02), learning (p = 0.05) and probability of ADHD (p = 0.04) in children who did not meet criteria for combined hyperactivity and inattention. Therefore, the New-Zealand green-lipped mussel extract PCSO-524® may be beneficial in reducing levels of hyperactivity and inattention in children and adolescents with clinical and subclinical symptoms of ADHD.

 

 

 

Kean JD, Sarris J, Scholey A, Silberstein R, Downey LA, Stough C. Reduced inattention and hyperactivity and improved cognition after marine oil extract (PCSO-524®) supplementation in children and adolescents with clinical and subclinical symptoms of attention-deficit hyperactivity disorder (ADHD): a randomised, double-blind, placebo-controlled trial. Psychopharmacology (Berl). 2016 Dec 5.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…
     

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Wednesday, January 4, 2017

Dioscorea japonica has beneficial effect on lipid metabolism in a high cholesterol diet.

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

This in vivo study on rats investigated the effects of dietary Japanese yam (Dioscorea japonica Thunb.) on lipid metabolism.

Male Wistar rats were fed a high-cholesterol diet for 6 weeks and then supplemented with 26% of Japanese yam or 0.5% of its constituent diosgenin for a further 4 weeks of high-cholesterol feeding (C6-J4 and C6-D4 groups, respectively).

In the C6-J4 group, body weight gains significantly decreased, but skeletal muscle fiber sizes in quadriceps significantly increased compared with the other groups. Furthermore, Japanese yam supplementation resulted in the reduction of triglyceride contents in their liver, quadriceps, and intra-abdominal visceral fat.

 Effects of yam or diosgenin on lipid accumulation in livers of high-cholesterol diet-fed rats

Figure 1 & 2: Effects of yam or diosgenin on lipid accumulation in livers of high-cholesterol diet-fed rats (1) Liver cholesterol contents are shown as mg per g of liver (2) Liver TG contents are presented as mg per g of liver Data are presented as means ± SE of 6 rats. Letters indicate significant differences between groups, p < 0.05.

Diosgenin supplementation resulted in an increase in the numbers of skeletal muscle fibers and decrease in the fat accumulations in liver and of the lipid contents in quadriceps.

These results suggest that Japanese yam is more effective than diosgenin in reducing fat accumulation and improving cholesterol metabolism during chronic consumption of a high-cholesterol diet.

 

Kusano Y, Tsujihara N, Masui H, Kozai H, Takeuchi W. Consumption of Japanese Yam Improves Lipid Metabolism in High-Cholesterol Diet-Fed Rats. J Nutr Sci Vitaminol (Tokyo). 2016;62(5):350-360.

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

More information on www.nutraveris.com

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Thursday, December 29, 2016

Maslinic acid from olive fruit improves pain and quality of life in knee joint pain patients

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

This randomized, double-blind, and placebo-controlled trial examined the effects of a maslinic acid supplement (a bioactive pentacyclic triterpenoid), olive fruit extract (Olea europaea L.), on 20 middle-aged and elderly volunteers with mild knee joint pain.

Each subject (58 ± 7 years) received either olive fruit extract, containing 50 mg maslinic acid (n = 12), or placebo (n = 8) daily for 12 weeks and evaluated for pain and physical functions.

Although both groups exhibited improved pain visual analogue scale score and quality of life after supplementation, symptoms were better in the maslinic acid group than in the placebo group. After 12 weeks, maslinic acid group exhibited significant decrease in body weight and body mass index suggesting that maslinic acid affected the weight of volunteers with mild knee joint pain.

Therefore, olive products containing maslinic acid may be useful as a new preventive and therapeutic food ingredient for arthritic diseases.

VAS joint pain in maslinic acid group compared to the placebo group

Fukumitsu S, Villareal MO, Aida K, Hino A, Hori N, Isoda H, Naito Y. Maslinic acid in olive fruit alleviates mild knee joint pain and improves quality of life by promoting weight loss in the elderly. J Clin Biochem Nutr. 2016 Nov;59(3):220-225.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

More information on www.nutraveris.com

Contactez nos experts scientifiques et réglementaires à:  NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87