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The aim of this study was to determine the antifatigue active fraction from Abelmoschus esculentus.
360 Kunming male mice were randomly divided into nine subgroups: normal control subgroup, model subgroup, positive subgroup and the ethanol extracts of A. esculentus with high dose (3.2 g/kg) subgroup, medium dose (1.6 g/kg) subgroup and low dose (0.8 g/kg) subgroup, the polysaccharides of high dose (3.2 g/kg) subgroup, medium dose (1.6 g/kg) subgroup, and the low dose (0.8 g/kg) subgroup. Compared with the model subgroup, other subgroups significantly prolonged swimming time, and high dose polysaccharides administration was the most effective (P < 0.01). High dose polysaccharides significantly increased liver glycogen, serum lactic acid, and serum urea (P < 0.01) in mice. In contrast with model group, the high dose polysaccharides administration could also significantly elevated the parameters of testicles and epididymis (P < 0.01). The results demonstrated that both the ethanol extracts and polysaccharides of A. esculentus have antifatigue effects.
Li YX, Yang ZH, Lin Y, Han W, Jia SS, Yuan K. Antifatigue Effects of Ethanol Extracts and Polysaccharides Isolated from Abelmoschus esculentus. Pharmacogn Mag. 2016 Jul-Sep;12(47):219-24..
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