Nutraveris

Category 'News'

Thursday, August 17, 2017

Bifidobacterium animalis and constipation

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

This randomized, double-blind controlled trial aim was to evaluate the effect of consumption of a probiotic fermented milk beverage containing Bifidobacterium animalis on the symptoms of constipation.

49 female patients aged 20 to 50 years and diagnosed with constipation according to the ROME III criteria (Diagnostic Criteria for Functional Gastrointestinal Disorders) and the Bristol Stool Form Scale received the probiotic fermented milk beverage or a non-probiotic milk as control, during 60 days.

The intervention group showed improvement in the following criteria: straining during a bowel movement (P <0.001), feeling of incomplete evacuation (P <0.001) and difficulty in passing stool (P <0.014), in addition to Bristol scale results (P <0.001). In the control group, improvements were observed in the following criteria: straining during a bowel movement (P <0.001), feeling of incomplete evacuation (P <0.001) and difficulty in passing stool (P <0.025), in addition to Bristol scale results (P <0.001).

 

Bifidobacterium and constipation

 

 

No statistically significant post-intervention differences were observed between the two groups for the Rome III criteria and Bristol scale. Authors concluded the consumption of milk resulted in the improvement of constipation symptoms, regardless of the probiotic culture.

 

 

Moreira TR, Leonhardt D, Conde SR. Influence of drinking a probiotic fermented milk beverage containing Bifidobacterium animalis on the symptoms of constipation. Arq Gastroenterol. 2017 May 25:0.  

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

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With NOL let’s : 

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  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

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Tuesday, August 15, 2017

Bitter melon for the regulation of lipid metabolism: a rat’s study

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

Bitter melon (Momordica charantia, also known as karela) is known to have hypoglycemic effects in type 1 and 2 diabetic rodents, and to lower blood lipids in streptozotocin-induced diabetic rats. This study wanted to clarify the metabolic effects of bitter melon and to examine its mechanism of action.

 

Rats have been divided into four groups:

1) control animal,

2) cholesterol-fed rats (40 mg/kw bw),

3) M. charantia group (5 g/kg bw) or

4) the combination of cholesterol and M. charantia. Supplements were given for 10 weeks.

 

Results confirmed the beneficial effects of M. charantia on blood lipids. Moreover, the supplementation has reverted the hepatic histopathological changes observed with cholesterol intakes, including cholesterol clefts, necrosis, karyolysis and sever congestion of portal blood vessel.

 

 Karela and hypercholesterolemia

 

The analysis of gene expression showed that bitter melon was able to normalize the expression of several genes affected by the cholesterol supplementation, and notably the PPARα, PPAR γ, Fatty Acid Synthase, and more globally genes involved in lipolysis, lipogenesis and cholesterol metabolism. Therefore, bitter melon may be a potential supplement for the management of diabetes and obesity-related metabolic disorders. 

 

Saad DY, Soliman MM, Baiomy AA, Yassin MH, El-Sawy HB. Effects of Karela (Bitter Melon; Momordica charantia) on genes of lipids and carbohydrates metabolism in experimental hypercholesterolemia: biochemical, molecular and histopathological study. BMC Complement Altern Med. 2017 Jun 17;17(1):319.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Thursday, August 10, 2017

A systematic review brings evidence on omega 3 fatty acids benefits on arthritic pain

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The aim of this systematic review was to investigate the effect of ω-3 PUFAs on arthritic pain.

Eighteen randomized controlled trials published between 1985 and 2013 involving 1143 patients were included. Dosage of ω-3 PUFAs used was 2.1 to 9.1 g/d, with study durations of 12 to 52 weeks. Ten studies supported the hypothesis that there is a reduction in patient or physician assessment of pain associated with rheumatoid arthritis after intake of ω-3 PUFAs. Eight studies found no statistically significant effect of ω-3 PUFAs on arthritic pain.

 

omega 3 fatty acids benefits on arthritic pain

PRISMA flow diagram showing multistage search strategy and study selection

 

ω-3 PUFAs may have a therapeutic role in decreasing pain associated with rheumatoid arthritis, with doses of 3 to 6 g/d appearing to have a greater effect.

 

Abdulrazaq M, Innes JK, Calder PC. Effect of ω-3 polyunsaturated fatty acids on arthritic pain: A systematic review. Nutrition. 2017 Jul-Aug;39-40:57-66.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Tuesday, August 8, 2017

A bilberry extract may improve tear secretion in subjects with dry eyes.

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

This randomized, double-blinded and placebo-controlled study examined the effects of a bilberry extract in subjects with dry eyes.

The supplementation consisted in a bilberry dried standardized extract derived from fresh frozen fruits (Mirtoselect®): 21 subjects received the supplement or a placebo for 4 weeks.

 

bilberry

 

Schirmer’s test values indicating the volume of tear secretion were significantly improved in the bilberry extract group (p=0.019), whereas no significant changes were observed in the placebo group. A subset analysis revealed that Mirtoselect® could be more effective in subjects with higher tendency of dry eye.

 

Therefore, a bilberry extract may improve tear secretion and be consequently useful for the management of dry eyes.  

 

 

Riva A, Togni S, Franceschi F, Kawada S, Inaba Y, Eggenhoffner R, Giacomelli L. The effect of a natural, standardized bilberry extract (Mirtoselect®) in dry eye: a randomized, double blinded, placebo-controlled trial. Eur Rev Med Pharmacol Sci. 2017 May;21(10):2518-2525.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Thursday, August 3, 2017

Chlorogenic acid increases fat oxidation.

NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

Chlorogenic acid is the most abundant polyphenol in coffee. It has been shown that chlorogenic acid may reduce body weight and fat mass. In this study, the effects of chlorogenic acid on energy metabolism and sleep have been studied.

 

cup of coffee

 

Nine subjects (4 men and 5 women) have been recruited for this double-blinded, randomized, placebo-controlled and crossover study. They received a beverage containing 0 or 600 mg of chlorogenic acid for 5 days.

 

 

Results showed that cholorogenic acid increases fat oxidation in comparison to control (122 ± 20 kcal/8h vs. 81 ± 19 kcal/8h, p < 0.05).

Moreover, the supplementation has reduced sleep latency, without any effect on sleep architecture.

Chlorogenic acid increase consequently fat oxidation in humans, an effect that confirms the interest of coffee consumption for the management of body weight and fat mass.

 

 

Park I, Ochiai R, Ogata H, Kayaba M, Hari S, Hibi M, Katsuragi Y, Satoh M, Tokuyama K. Effects of subacute ingestion of chlorogenic acids on sleep architecture and energy metabolism through activity of the autonomic nervous system: a randomised, placebo-controlled, double-blinded cross-over trial. Br J Nutr. 2017 Apr;117(7):979-984.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87