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Thursday, October 11, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The aim of this randomized, single-blind study was to test whether a supplementation with a tomato paste purèe could improve some haemodynamic parameters in healthy volunteers before and after a standardized fat meal (FM), for 7 days.

Tomato paste

Nineteen healthy male volunteers were randomized either to a low fiber diets (LFD) and tomato paste arm (80 g of tomato paste /day) for 7-days, or to a control arm (LFD-only) with a 2-week washout period.

The difference in Stiffness Index was increased in the LFD and tomato paste + FM-arm, as compared to the LFD-only + FM arm at both 2 and 3.5 h points. After the FM, in both arms, at 2 h, a reduction in the Reflection Index and an increase in heart rate were observed. Interestingly, only in the LFD and tomato paste + FM-arm, some haemodynamic changes were detectable at 2 h; notably, there was an increase in brachial artery diameter and a reduction in diastolic blood pressure.

 

Tomato paste acutely modifies some haemodynamic parameters triggered by fat meal, suggesting possible haemodynamic beneficial effects in people consuming tomatoes.

 

Dalbeni A, Treggiari D, Tagetti A, Bevilaqua M, Bonafini S, Montagnana M, Scaturro G, Minuz P, Fava C. Positive Effects of Tomato Paste on Vascular Function After a Fat Meal in Male Healthy Subjects. Nutrients. 2018 Sep 15;10(9).

 

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Monday, October 8, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The authors of this study examined the neuroprotective effects of walnut peptides (Juglans regia). They used a rat model of memory impairment due to sleep deprivation. The walnut protein hydrolysate had significant effects on behavioral performance in the Marris water maze test, a task used to study spatial learning and memory. These effects were associated with an improvement in antioxidant defenses with the walnut preparation.

 

Walnut

 

In addition, the authors showed that three neuroprotective peptides (GGW, VYY and LLPF) had significant neuroprotective properties in PC12 cells treated with glutamate. Once again, these peptides had strong radical scavenging properties.

 

In conclusion, walnut peptides may be used for the management of neurodegenerative disorders characterized by memory deficits. However, these pre-clinical results should be confirmed in humans.

 

 

Wang S, Su G, Zhang Q, Zhao T, Liu Y, Zheng L, Zhao M. Walnut (Juglans regia) peptides reverse sleep deprivation-induced memory impairment in rat via alleviating oxidative stress. J Agric Food Chem. 2018 Sep 18.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

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With NOL let’s : 

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  • Check if your already existing formulas are still compliant with the in force regulations

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  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

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Friday, October 5, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

To determine the effects of cumin supplementation (Cuminum cyminum L.) on plasma lipids, the authors of this systematic review and meta-analysis have compiled results from 6 randomized and controlled studies (376 subjects).

 

cumin

 

They showed that cumin supplementation can reduce plasma concentration of total cholesterol (mean difference (MD) = -10.90 mg/dL, 95% CI: -21.39, -0.42, p = 0.042) and LDL-cholesterol (MD = -6.94 mg/dL, 95% CI: -11.53, -2.35, p = 0.003) in comparison to control treatment.

In addition, HDL-cholesterol levels were found to be increased by the supplementations (MD = 3.35 mg/dL, 95% CI: 1.58, 5.12, p < 0.001). Finally, cumin tended to decreased triglycerides levels (MD = -20.48 mg/dL, 95% CI: -41.23, -0.26, p = 0.053).

 

In conclusion, this meta-analysis suggest that cumin supplementation is effective for the management of dyslipidemia.

 

Hadi A, Mohammadi H, Hadi Z, Roshanravan N, Kafeshani M. Cumin (Cuminum cyminum L.) is a safe approach for management of lipid parameters: A systematic review and meta-analysis of randomized controlled trials. Phytother Res. 2018 Aug 8.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

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With NOL let’s : 

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  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

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Wednesday, October 3, 2018
Category : TRAINING | Author : experts | Comment : No Comments
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Sorry, this entry is only available in French.

Tuesday, October 2, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

Probiotics are mainly known for their effects on digestive health or immune function. The aim of this randomized, double-blinded and placebo-controlled study was to examine the effects of heat-killed Lactobacillus paracasei KW3110 on ocular disorders caused by visual display terminal (VDT) loads.

62 healthy subjects have received a placebo or the probiotic for 8 weeks. The main outcome was the change in ocular fatigue induced by VDT.

ocular fatigue

A small in vitro study has shown that L. paracasei was able to prevent blue light-induced human retinal cell death. Results of the clinical study showed that the supplementation reduce VDT-induced eye fatigue. At 4 weeks, a lower fatigue was measured in a sub-group of subjects with the higher degred of eye fatigue (p = 0.02).

 

Therefore, this study provides preliminary results on a potential ocular benefits of a supplementation in heat-killed Lactobacillus paracasei KW3110.

 

 

Morita Y, Jounai K, Miyake M, Inaba M, Kanauchi O. Effect of Heat-Killed Lactobacillus paracasei KW3110 Ingestion on Ocular Disorders Caused by Visual Display Terminal (VDT) Loads: A Randomized, Double-Blind, Placebo-Controlled Parallel-Group Study. Nutrients. 2018 Aug 9;10(8).

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
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  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

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Contact our Scientific & Regulatory experts at NUTRAVERIS

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