Nutraveris
Tuesday, September 11, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

This aim of this pilot study was to examine the effects of a novel proprietary delivery form of quercetin (Phytosome®) in amateur triathlon athletes. 48 subjects have been enrolled. They received no supplement (n = 25) or 250 mg Phytosome® twice daily for 14 days. The training included repetition of a run 8 times in 14 days.

triathlon athletes

Results showed an improvement in the time to complete the run in the supplemented group in comparison to control (-11.3% vs. -3.9%, p < 0.05). Moreover, training was considered as more valuable in the quercetin group in comparison to control (p < 0.05). In addition, post-run muscular pain, cramps, localized pain and post-exercise recovery time was all considered better with the supplementation (p < 0.05).

 

Therefore, this pilot study suggest that Phytosome® may improve physical performance in athletes. These results should be confirmed in larger well-designed clinical trials.

 

 

Riva A, Vitale JA, Belcaro G, Hu S, Feragalli B, Vinciguerra G, Cacchio M, Bonanni E, Giacomelli L, Eggenhöffner R, Togni S. Quercetin phytosome® in triathlon athletes: a pilot registry study. Minerva Med. 2018 Aug;109(4):285-289.

 

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Thursday, September 6, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The aim of this work was to investigate whether raspberry consumption can improve vascular function and to understand which phenolic metabolites may be responsible for the effects.

A 3 arm double-blind randomized controlled crossover human intervention trial was conducted in 10 healthy males. Flow-mediated dilation (FMD) was measured at baseline, 2 h, and 24 h post-consumption of 200 g and 400 g of red raspberries containing 201 or 403 mg of total (poly)phenols, or a matched control drink.

 

Raspberries

 

Raspberry (poly)phenol metabolites were analyzed in plasma and urine by UPLC-QTOF mass spectrometry using authentic standards. Significant improvements in FMD were observed at 2 h (1.6% (95%CI 1.2, 1.9) and 1.2% (95% CI 0.8, 1.5)) and 24 h (1.0% (95% CI 0.6, 1.2) and 0.7% (95%CI 0.2, 0.9)) post-consumption of the 200 and 400 g raspberry drinks as compared to control, respectively. Plasma ellagic acid, urolithin A-3-glucuronide and urolithin A-sulfate correlated with the improvements in FMD at 2 and 24 h post consumption, respectively.

Consumption of dietary achievable amounts of red raspberries acutely improves endothelial function up to 24 h and ellagitannins may be responsible for the observed effect.

 

 

Istas G, Feliciano RP, Weber T, Garcia-Villalba R, Tomas-Barberan F, Heiss C, Rodriguez-Mateos A  Plasma urolithin metabolites correlate with improvements in endothelial function after red raspberry consumption: A double-blind randomized controlled trial. Arch Biochem Biophys. 2018 Aug 1;651:43-51.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

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With NOL let’s : 

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  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

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Tuesday, September 4, 2018
Category : TRAINING | Author : experts | Comment : No Comments
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Sorry, this entry is only available in French.

Sorry, this entry is only available in French.

Tuesday, August 28, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The aim of this crossover and single blind study was to determine the effects of a single intake of hazelnut and cocoa spread (60 g) on flow-mediated dilation and oxidative stress in comparison to milk chocolate.

20 smokers have been enrolled and all parameters have been assessed at baseline and 2h after chocolate ingestion.

hazelnuts and cocoa

Results showed that flow-mediated dilation and NOx increased after the hazel nut and chocolate spread (p < 0.001 and p = 0.016 respectively), while serum isoprostanes and Nox2 activation decreased (p = 0.03 for both). No change was observed after the milk chocolate consumption.

 

Thus, a hazelnut and chocolate spread improves flow-mediated dilation, with a mechanism potentially involving downregulation of oxidative stress and eventually increased NO generation in smokers.

 

 

Loffredo L, Perri L, Battaglia S, Nocella C, Menichelli D, Cammisotto V, Novo M, Carnevale R, Violi F. Hazelnut and cocoa spread improves flow-mediated dilatation in smokers. Intern Emerg Med. 2018 Jul 20.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

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  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87