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Thursday, July 5, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

Açai berries are rich in various polyphenols, which may have anti-diabetic properties. The purpose of this randomized and placebo-controlled study was to determine the effects of an açai beverage in patients with metabolic syndrome. 37 subjects received a control beverage or an acai beverage 325 mL twice daily, providing 1136 mg/L gallic acid equivalent) for 12 weeks.

Açai

Only two markers have been significantly affected by the açai consumption: the plasma level of IFN-γ (p = 0.0141) and the urinary level of 8-isoprostane (p = 0.0099). Parameters related to lipid and glucose metabolism remained unaffected by the supplementation.

 

Therefore, despite its recognition as “super-fruit”, açai may only provide few benefits for peole with metabolic syndrome.

 

 

Kim H, Simbo SY, Fang C, McAlister L, Roque A, Banerjee N, Talcott ST, Zhao H, Kreider RB, Mertens-Talcott SU. Açaí (Euterpe oleracea Mart.) beverage consumption improves biomarkers for inflammation but not glucose- or lipid-metabolism in individuals with metabolic syndrome in a randomized, double-blinded, placebo-controlled clinical trial. Food Funct. 2018 May 31.

 

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Tuesday, July 3, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The purpose of this investigation was to determine if β-Alanine supplementation improved the adaptive response to five weeks of a resistance training program.

 

sportsmen

To do so, thirty healthy, strength-trained individuals were randomly assigned to the experimental group placebo (PLA) or β-Alanine. Over 5 weeks of strength training, subjects in β-Alanine took 6.4 g/day of β-Alanine as 8 × 800 mg doses each at least 1.5 h apart. The training program consisted of 3 sessions per week in which three different leg exercises were conducted as a successive exercice circuit.

 

Branched amino acids

 

The variables measured were average velocity, peak velocity, average power, peak power, and load in kg in a back squat, incremental load, one-repetition maximum (1RM) test. In addition, during the rest period, jump ability (jump height and power) was assessed on a force platform.

Significantly greater training improvements were observed in the β-Alanine group versus PLA group (p = 0.045) in the variables average power at 1RM (BA: 42.65%, 95% CI, 432.33, and 522.52 VS. PLA: 21.07%, 95% CI, 384.77, 482.19) and average power at maximum power output (p = 0.037). The pre- to post training average power gain produced at 1RM in BA could be explained by a greater maximal strength gain, or load lifted at 1RM (p = 0.014) and in the number of sets executed (p = 0.025) in the incremental load test (BA: 2.79 sets, 95% CI, 2.08, and 3.49 VS. PLA: 1.58 sets, 95% CI, 0.82, 2.34).

The authors conclude that β-Alanine supplementation was effective at increasing power output when lifting loads equivalent to the individual’s maximal strength or when working at maximum power output.

 

 

Effects of β-alanine supplementation during a 5-week strength training program: a randomized, controlled study. Maté-Muñoz JL, Lougedo JH, Garnacho-Castaño MV, Veiga-Herreros P, Lozano-Estevan MDC, García-Fernández P, de Jesús F, Guodemar-Pérez J, San Juan AF, Domínguez R. J Int Soc Sports Nutr. 2018 Apr 25;15:19..

 

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Thursday, June 28, 2018
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This trial compared the effects of lavender and bitter orange on anxiety in postmenopausal women.

To do so, postmenopausal women were allocated into one of two intervention groups or a control group (n = 52 per group) in a 1:1:1 ratio using a randomized block design. Intervention groups received 500 mg capsules containing only bitter orange or lavender flower powder, and the control group received 500 mg capsules containing starch.

bitter orangelavender flower

 

The results showed no significant difference in mean state anxiety (P = 0.254) and trait anxiety (p = 0.972) score among the three groups before the intervention.

Bitter orange significantly reduced the mean state-anxiety scores compared with the control group.

Lavender significantly reduced the mean state-anxiety scores compared with the control group as well [aMD: -2.45 (95% CI -4.13 to -0.77)] and Bitter orange significantly reduced the mean trait-anxiety scores compared with the control group [aMD: -1.76 (95% CI -3.45 to -0.06)]. Lavender significantly reduced the mean trait-anxiety scores compared with the control group.

Note that, there was no significant difference between bitter orange and lavender groups after intervention in the mean trait-anxiety (p = 0.731) or state-anxiety scores (p = 0.578).

The authors conclude that positive effects of bitter orange and lavender on anxiety in postmenopausal women suggests that they can be used to decrease anxiety in such women.

 

Farshbaf-Khalili A, Kamalifard M, Namadian M. Comparison of the effect of lavender and bitter orange on anxiety in postmenopausal women: A triple-blind, randomized, controlled clinical trial. Complement Ther Clin Pract. 2018 May;31:132-138.

 

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Tuesday, June 26, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The aim of this double-blinded, randomized and placebo-controlled study was to assess the effects of omega 3 fatty acids in overweight/obese women with depression. 65 women have been enrolled in this 12-week trial. They received a placebo or omega 3 fatty acids (1080 mg EPA and 720 mg DHA per day).

Omega 3 fatty acids

Results showed that the supplementation reduced depressive symptoms compared with placebo (p = 0.05). Moreover, a reduction in body weight has been measured in the supplemented group in comparison to placebo (-3.07 ± 3.4 kg vs. -1.16 ± 2.7 kg, p = 0.049). However, a follow-up visit one month after the end of the supplementation showed that omega 3 fatty acids were not effective to prevent weight regain.

 

Nevertheless, these results suggest that omega 3 fatty acids may be a safe solution to reduce body weight and depression in overweight or obese women.

 

 

Keshavarz SA, Mostafavi SA, Akhondzadeh S, Mohammadi MR, Hosseini S, Eshraghian MR, Chamari M. Omega-3 supplementation effects on body weight and depression among dieter women with co-morbidity of depression and obesity compared with the placebo: A randomized clinical trial. Clin Nutr ESPEN. 2018 Jun;25:37-43.

 

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Thursday, June 21, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

Since type 2 diabetes is related to the gut microbiota, the authors of this randomized and placebo-controlled study wished to determine the effects of L. casei (108 CFU/day for 8 weeks) on blood glucose and insulin levels, and on serum sirtuin 1 and fetuin-A. 40 patients have been included in the study.

Lactobacillus casei

Results showed that L. casei induced significant decreases in fasting blood glucose (-28.32 [-50.23 to -6.41], p = 0.013), insulin concentration (-3.12 [-5.90 to -0.35], p = 0.028), and insulin resistance (-32.31 [-55.09 to -9.54], p = 0.007), all in comparison to placebo. A non-significant reduction in HbA1c has been also reported (-0.45 [-0.96 to 0.05], p = 0.077). These effects may be explained by the increase in sirtuin level (p = 0.040) and the decrease in fetuin-A level (p = 0.023) measured at the end of the trial in the supplemented group in comparison to placebo.

 

In conclusion, Lactobacillus casei may improve glycemic response in subjects with type 2 diabetes. The mechanism of action may involve the sirtuin 1 and fetuin-A levels.

 

 

Khalili L, Alipour B, Asghari Jafar-Abadi M, Faraji I, Hassanalilou T, Mesgari Abbasi M, Vaghef-Mehrabany E, Alizadeh Sani M. The Effects of Lactobacillus casei on Glycemic Response, Serum Sirtuin1 and Fetuin-A Levels in Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Trial Iran Biomed J. 2018 May 27.

 

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

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With NOL let’s : 

  • Formulate new innovative products
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  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

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