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Tuesday, September 4, 2018
Category : Formation | Author : experts | Comment : No Comments
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Sorry, this entry is only available in French.

Sorry, this entry is only available in French.

Tuesday, August 28, 2018
Category : News, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The aim of this crossover and single blind study was to determine the effects of a single intake of hazelnut and cocoa spread (60 g) on flow-mediated dilation and oxidative stress in comparison to milk chocolate.

20 smokers have been enrolled and all parameters have been assessed at baseline and 2h after chocolate ingestion.

hazelnuts and cocoa

Results showed that flow-mediated dilation and NOx increased after the hazel nut and chocolate spread (p < 0.001 and p = 0.016 respectively), while serum isoprostanes and Nox2 activation decreased (p = 0.03 for both). No change was observed after the milk chocolate consumption.

 

Thus, a hazelnut and chocolate spread improves flow-mediated dilation, with a mechanism potentially involving downregulation of oxidative stress and eventually increased NO generation in smokers.

 

 

Loffredo L, Perri L, Battaglia S, Nocella C, Menichelli D, Cammisotto V, Novo M, Carnevale R, Violi F. Hazelnut and cocoa spread improves flow-mediated dilatation in smokers. Intern Emerg Med. 2018 Jul 20.

 

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More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Thursday, August 23, 2018
Category : News, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The aim of the present registry was to investigate the influence of Robuvit® (Horphag Research, Ltd.), an extract from wood of the French oak (Quercus robur), on a group of subjects presenting with mood disorders, oxidative stress, fatigue, and insomnia.

rubovit

40 patients were recruited from a selection of patients with high oxidative stress levels as assessed with the d-ROMs test. 22 subjects formed the control group. The remaining 18 subjects received 3 capsules of Robuvit® 100 mg per day, for 8 weeks.

Tolerability to the supplementation with Robuvit® was overall good, and no safety concerns were raised. Mood tests showed a significant general improvement in 13 out of 16 items of the BMIS (Brief Mood Introspection Scale, P<0.05) in the active treatment group. Oxidative stress levels decreased significantly with Robuvit® supplementation after 4 and 8 weeks. Fatigue and insomnia score were also significantly better in supplemented subjects (P<0.05).

The observed decrease in oxidative stress levels in our patients is probably the result of the antioxidative activity of Robuvit®, and of its active metabolites, the urolithins and ellagic acid.

 

Belcaro G, Saggino A, Cornelli U, Luzzi R, Dugall M, Hosoi M, Feragalli B, Cesarone MR. Improvement in mood, oxidative stress, fatigue, and insomnia following supplementary management with Robuvit®. J Neurosurg Sci. 2018 Aug;62(4):423-427.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Tuesday, August 21, 2018
Category : News, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

The aim of this 1-year randomized controlled study was to examine the effect of a Mediterranean-like dietary pattern on indexes of inflammation and secondary endpoints, including bone mineral density (BMD) and biomarkers of bone and collagen degradation in elderly Europeans.

Mediterranean-diet

 

Subjects in the intervention group consumed the Mediterranean diet for 1 year, with supplies of foods including whole-grain pasta, olive oil, and a vitamin D3 supplement (10 µg/d). Participants in the control group were provided with leaflets on healthy eating.

1294 elderly were recruited to the study and 1142 completed the trial. The Mediterranean dietary pattern had no effect on BMD. Serum 25-hydroxyvitamin D significantly increased and parathyroid hormone decreased (P < 0.001) in the MD compared with the control group. Subgroup analysis of individuals with osteoporosis at baseline showed that the Mediterranean-diet attenuated the expected decline in femoral neck BMD (P = 0.04).

Mediterranean-like diet together with vitamin D3 supplements (10 µg/d) significantly reduced the rate of loss of bone at the femoral neck in individuals with osteoporosis.

Jennings A, Cashman KD, Gillings R, Cassidy A, Tang J, Fraser W, Dowling KG, Hull GLJ, Berendsen AAM, de Groot LCPGM, Pietruszka B, Wierzbicka E, Ostan R, Bazzocchi A, Battista G, Caumon E, Meunier N, Malpuech-Brugère C, Franceschi C, Santoro A, Fairweather-Tait SJ. A Mediterranean-like dietary pattern with vitamin D3 (10 µg/d) supplements reduced the rate of bone loss in older Europeans with osteoporosis at baseline: results of a 1-y randomized controlled trial. Am J Clin Nutr. 2018 Jul 11.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

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