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Wednesday, April 11, 2018
Category : TRAINING | Author : experts | Comment : No Comments
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Tuesday, April 10, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

Extra virgin olive oil is known to reduce post-prandial glycaemia. To better understand the mechanisms of action, the authors of this study examined the effects of oleuropein on post-prandial glycaemia.

olive oil

20 healthy subjects have been included in this randomized, placebo-controlled and crossover study. They received a placebo or 20 mg oleuropein immediately before lunch. After Two hours, subjects who received oleuropein had lower blood glucose and dipeptidyl-peptidase 4 activity, and higher insulin and glucagon-like peptide-1 levels compared to placebo. Moreover, Nox2 activity, 8-iso-PGF2α and platelet p47phox phosphorylation were lower after oleuropein than after placebo.

 

Consequently, the authors hypothesized that oleuropein improves post-prandial glycaemia via hampering Nox2-derived oxidative stress.

 

Carnevale R, Silvestri R, Loffredo L, Novo M, Cammisotto V, Castellani V, Bartimoccia S, Nocella C, Violi F. Oleuropein, a component of extra virgin olive oil, lowers post-prandial glycaemia in healthy subjects. Br J Clin Pharmacol. 2018 Mar 26.

 

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Thursday, April 5, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

Fennel is traditionally used for the management of dysmenorrhea. However, its effects on menstrual bleeding are unclear. The aim of this systematic review and meta-analysis was to examine the available scientific evidences on the effects of fennel on menstrual bleeding and duration of menstrual bleeding.

fennel

Only 4 trials have been included in the meta-analysis. The results showed that using fennel caused a significant increase in mean menstrual bleeding in the first cycle after treatment in the intervention group compared to the control (standard mean difference: 0.46; 95 % CI: 0.18-0.73; p = 0.001; I2 = 9 %). However, it had no significant effect on menstrual bleeding in the second cycle after treatment (mean difference: 1.44; 95 % CI:-5.09 to 7.96; p = 0.67; I2 = 0 %).

 

These results suggest that fennel may increase menstrual bleeding in the first cycle of treatment, but not in a second cycle.

However, results are of low quality, and further research is required to clarify the effects of fennel on menstrual bleeding.

  

Abdollahi NG, Mirghafourvand M, Mollazadeh S. The effects of fennel on menstrual bleeding: A systematic review and meta-analysis. J Complement Integr Med. 2018 Mar 2.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
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  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

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Tuesday, April 3, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

This randomized, double-blinded and placebo-controlled study examined the effects of 600 mg of artichoke leaf extract on liver health in patients with non-alcoholic fatty liver disease (NAFLD). 100 subjects have been enrolled, and received the extract or a placebo for 2 months.

artichoke

In comparison to placebo, the artichoke leaf extract increased the hepatic vein flow (p < 0.001) and reduced the portal vein diameter (p < 0.001) and liver size (p < 0.001). This improvement in NAFLD was associated with reduction in serum ALT (p < 0.001) and AST (p < 0.001) levels, as total bilirubin.

Moreover, the extract reduced total, LDL- and HDL-cholesterol concentrations, as non-HDL-cholesterol and triglycerides concentrations.

 

Taking together, this study showed that an artichoke leaf extract (600 mg/day for 2 months) has beneficial effects on both ultrasound liver parameters and liver serum parameters, suggesting a potential clinical interest of such extracts for the management of NAFLD.

 

Panahi Y, Kianpour P, Mohtashami R, Atkin SL, Butler AE, Jafari R, Badeli R, Sahebkar A. Efficacy of artichoke leaf extract in non-alcoholic fatty liver disease: A pilot double-blind randomized controlled trial. Phytother Res. 2018 Mar 9.

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87

Tuesday, March 27, 2018
Category : NEWS, INGREDIENTS, INNOVATION, CLINICAL EVIDENCE | Author : experts | Comment : No Comments
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NOL, Nutraveris Online, the most efficient data solution to create, keep up-to-date and launch your products in the 28 EU member states, used for 10years by more than 500 industry leaders informs you:

 

The purpose of this systematic review was to explore the effects of chocolate consumption during pregnancy both on fetus and mother.

14 human studies, including 6639 women, have been selected. In addition, 9 animal studies have been analyzed by the authors.

 

Ten out of these 23 studies reported chocolate to be “beneficial”; five studies reported adverse effects, whereas eight studies declared chocolate as “neutral”.

CHOCOLATE

However, conclusions were that chocolate consumption may have acute stimulatory effects on fetal reactivity and chronic blood pressure lowering reducing effects in mother. Chocolate is non-teratogenic and does not affect reproductive indices. However, metabolic derangements in offsprings born to chocolate fed animals have been reported.

Consequently, pregnant females must be careful about consumption of cocoa and chocolate.

 

Latif R. Maternal and fetal effects of chocolate consumption during pregnancy: a systematic review. J Matern Fetal Neonatal Med. 2018 Mar 13:1-13.

 

 

This information has been sourced by NOL, a collaborative and complete tool which contains all Regulatory, Scientific and Marketing data

  • It solves all regulatory issues since it contains the required information on all ingredients authorized in the 28 European member states…on regulatory status, health claims, authority opinions
  • It protects your investments since it is updated in real time with reliable quality information analyzed and reviewed by our experts, available hotline.
  • It enables you to be the most responsive with monthly reports and live alerts and a personal use of the information with a report editing tool and customizable bookmarks.

With NOL let’s : 

  • Formulate new innovative products
  • Check if your already existing formulas are still compliant with the in force regulations
  • Adapt your existing formulas to the requirements of other European countries where you are willing to export them
  • Do scientific & regulatory & marketing monitoring which enable to anticipate the withdrawal of products, the safety issues, new interesting scientific studies, the arrival of new players on the market…

 

More information on www.nutraveris.com

Contact our Scientific & Regulatory experts at NUTRAVERIS

contact@nutraveris.com, +33 2 96 76 54 87